Invented a subcutaneous sensor to more accurately measure glucose levels

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  • Non-invasive and revolutionary technology presented as an option for diabetics

  • The sensor is able to track subtle changes in dielectric permittivity due to changes in blood glucose levels.

This has been revealed in a study conducted by the National Institute of Science and Technology in Ulsan (South Korea). New way to measure sugar level in the blood (BGL) no need to draw blood, this is a revolutionary technology and non invasive To measure blood glucose levels, using an electromagnetic wave (EM)-based glucose sensor inserted under the skin.

Their findings, published in the journal ‘Scientific Reports’, have attracted a lot of attention, as it eliminates the need for diabetic patients fingers prick constantly with glucose meter.

In this study, the research team proposed electromagnetic base sensor can be transplanted by subcutaneous route and that it is able to track subtle changes in dielectric permittivity due to changes in BGL. proposed sensor, which Occupies about one-fifth of the cotton swabIt can measure changes in the concentration of glucose in the interstitial fluid (LIS), the fluid that fills the spaces between cells.

“The present work is an attempt to electromagnetic-based implantable sensor, which can be an alternative to enzyme-based or optical glucose sensors. proposed implantable sensor not only overcome the loss of current continuous glucose monitoring systems (CGMS), such as their short lifetime, but it is also Improved accuracy of blood glucose prediction“, explained the research team.

Diabetes can be diagnosed when the fasting blood glucose level is 126 mg/dL or higher. A normal fasting glucose test result is less than 100 mg/dL. One of the main goals of diabetes treatment is maintaining blood sugar levels within a certain range, More than 400 million people around the world are living with diabetes and keep pricking their fingers several times a day to check their blood sugar levels.

research in development

Blood sugar detection has been extensively studied Various Alternative Methods of Finger Prick Method, such as enzyme-based or optical glucose sensors. However, they continue to struggle with long life, portability, and accuracy.

In this study, the research team Introduced semi-permanent and continuous blood sugar management Allows patients to enjoy quality life through proper treatment and management of diabetes, with low cost of ownership and without the pain of drawing blood. it is expected that This increases the use of CGMSWhich is currently only 5%.

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research team too performed an intravenous glucose tolerance test (IVGTT) and oral glucose tolerance test (OGTT) with implanted sensors in pigs and beagles in a controlled environment. According to the research team, early results from an in vivo proof-of-concept experiment showed a promising correlation between the BGL and the sensor’s frequency response.

“Our proposed sensor and system are in the early stages of development, Despite this, the results of the in vivo proof of concept show a promising correlation between the BGL and the frequency response of the sensor. In fact, the sensor shows the ability to follow the BGL trend. For the actual implantation of the sensor we must take into account biocompatible packaging and foreign body reactions (FBRs) for long-term applications. In addition, an improved sensor interface system is being developed.”

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