Antibody cocktail: the expert separates the facts from the myths

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Antibody Therapy Cocktail has been approved as a treatment for COVID-19 in high-risk patients with mild to moderate disease. In fact, in a very short time, it has become a widely used therapy, said Prof. Dr. Salil Bendre, chief of pulmonary medicine at Nanavati Max Super Specialty Hospital.

However, there are several misconceptions surrounding this effective treatment. Read on to learn more about this therapy, so you have no doubts about it, added Dr. Bendre.

What is the therapy about?

This therapy can be given in a combination of two monoclonal antibodies: Casirivimab and Imdevimab, which are human immunoglobulin G-1 (IgG1) monoclonal antibodies that tend to act against the SARS-CoV-2 virus leading to the Covid-19 spike protein. The antibody cocktail blocks the binding of the virus and does not allow it to enter the human cell, reduces the chances of hospitalization and helps speedy recovery in Covid patients. But there is not much awareness about this therapy, so not many people opt for it, the expert told indianexpess.com.

These are some common myths.

Myth: Anyone can opt for antibody cocktail therapy

Done: No, not everyone can be given the therapy. There are certain guidelines that an expert must follow. The therapy is suitable for adult Covid patients with mild to moderate symptoms. Guidelines for children vary: they must be over 12 years old, weigh around 40kg and be covid positive with higher chances of contracting a serious infection or requiring hospitalisation. In addition, older people, those with hypertension, cardiovascular diseases, chronic obstructive pulmonary disease, Sickle-cell anaemia, asthma, diabetes mellitus, obesity, chronic kidney disease, HIV, or immune deficiencies can be.

Myth: People with low oxygen levels may opt for antibody cocktail therapy

Done: Casirivimab and Imdevimab it cannot be used in patients who require oxygen therapy or are hospitalized. Antibody cocktail therapy is known to be safe and effective in the successful treatment of Covid-19 when it comes to patients with mild to moderate infection. Your doctor will decide if you should take it or not.

Myth: This therapy can be administered by any doctor

Done: No, this therapy can also be administered by an expert who has complete knowledge of how it works. It is administered intravenously or subcutaneously within 48 to 72 hours of infection and within seven days, according to the OPD. “This therapy is a godsend for moderately ill covid patients,” Dr. Bendre said.

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